Test investigation
TTG
Laboratory offering test
NNUH
Units
IU/mL
Also known as/Frequency of test
Coeliac Antibodies, IgA tissue Transglutaminase (IgA Ttg) or Endomysial Antibodies; Endomysium Antibodies; IgA Endomysial Antibodies
Indications
IgA tTg is the first line test for coeliac disease; a positive result should be confirmed with a request for EMA. If IgA deficiency is suspected (laboratory findings) total immunoglobulin/electrophoresis and IgG tTG will be requested. All these tests have a good sensitivity and specificity for Coeliac disease if the patient is on a gluten containing diet (2 gluten containing meals daily for 6 weeks)
Sample type
Serum
Turnaround times (TAT) Urgent/Routine/GP or OPD
2 working days
Reference intervals
0.0 – 7.0 IU/mL Negative 7.0 – 10.0 IU/mL Equivocal > 10.0 IU/mL Positive
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