Smooth Muscle Antibodies

Test/Investigation

Smooth Muscle Antibodies

Site(s) or Laboratory offering Test/Investigation

NNUH

Units

Titre

Also Known as/Frequency of Test

SMA, SMA Titre, F-Actin, Liver autoantibodies, Autoimmune screen

Indications

Smooth muscle auto-antibodies are associated with autoimmune chronic active hepatitis (CAH). Sensitivity of 70% and up to 50% of patients with primary biliary cirrhosis. These antibodies often occur as a 'false positive' in patients with viral infections. Low titre results in patients with normal liver function are of limited clinical significance

Comments/Precautions

This test may be reflexed from findings on autoantibody screen

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 working days

Reference intervals (adult unless stated)

Negative

If UKAS Accredited Test indicate at which site

Y NNUH