Smooth Muscle Antibodies

Test investigation

Smooth Muscle Antibodies

Laboratory offering test

NNUH

Units

Titre

Also known as/Frequency of test

SMA, SMA Titre, F-Actin, Liver autoantibodies, Autoimmune screen

Indications

Smooth muscle auto-antibodies are associated with autoimmune chronic active hepatitis (CAH). Sensitivity of 70% and up to 50% of patients with primary biliary cirrhosis. These antibodies often occur as a 'false positive' in patients with viral infections. Low titre results in patients with normal liver function are of limited clinical significance

Comments precautions

This test may be reflexed from findings on autoantibody screen

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 working days

Reference intervals

Negative