Skin Antibodies

Test investigation

Skin Antibodies

Laboratory offering test

NNUH

Units

N/A

Also known as/Frequency of test

Pemphigus; Pemphigoid; Skin, Epidermal Antibodies, split skin

Indications

These are rare, but serious autoimmune skin diseases. Bullous Pemphigoid (70% antibody positive, correlates with disease activity) - tense blisters, mucosa rarely involved. Pemphigus Vulgaris (90% antibody positive, no disease correlation) - flaccid blisters, mucosa often involved. Immunofluorescence of a skin biopsy should also be performed as both assays can give false negative results

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

1 week

Reference intervals

Negative