Serum free light chains

Test investigation

Serum free light chains

Laboratory offering test

NNUH

Units

mg/L

Also known as/Frequency of test

SFLC, Free Kappa, Free Lambda, Light Chain Ratio

Indications

This test detects the presence of kappa and lambda free light chains, and expresses these as a ratio, the sFLC ratio. It contributes to a clinical and laboratory features in the diagnosis of myeloma and other B cells dyscrasias. High and low ratios are abnormal as this reflects a skewed proportion of lambda or kappa light chains.

Comments precautions

This test may be reflexed from findings on serum electrophoresis

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

5 working days

Reference intervals

Kappa = 6.7 – 22.4 mg/L Lambda = 8.3 27.0 mg/L Kappa/Lambda Ratio = 0.31 – 1.56