Neuronal blot

Test/Investigation

Neuronal blot

Site(s) or Laboratory offering Test/Investigation

Referral laboratory

Also Known as/Frequency of Test

Paraneoplastic Antibody, Hu, Ri, Yo, PNMA2, TrMa2/Ta, Amphiphysin, CV2, Zic4, SOX1, ANNA-1, ANNA-2

Indications

Identifies antibodies associated with paraneoplastic neurological syndromes. The presence of these antibodies can be associated with an underlying tumour.

Comments/Precautions

Initial screen on IIF with all positives confirmed on immunoblot. CSF samples will not be accepted.

Ideal sample age for accurate results/Maximum acceptable sample age (at the time of analysis)

Referred outside of EPA

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 weeks

Reference intervals (adult unless stated)

Negative