Myelin Associated Glycoprotein

Test/Investigation

Myelin Associated Glycoprotein

Site(s) or Laboratory offering Test/Investigation

Referral laboratory

Also Known as/Frequency of Test

MAG, Anti-MAG

Indications

Myelin Associated Glycoprotein (MAG) autoantibodies are associated with peripheral neuropathy and IgM paraproteinaemia. Antibodies may respond favourably to therapeutic intervention. Testing for the presence of these autoantibodies is useful for diagnosis as well as monitoring of therapy

Comments/Precautions

Referred outside of EPA.

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

4 weeks

Reference intervals (adult unless stated)

< 1,000 BTU No detection of anti-MAG IgM antibody
1,000 - 2,000 BTU Weak insignificant result
2,001 - 4,000 BTU Doubtful result to be interpreted with clinical and biological feature (monoclonal IgM?); to be checked later
4,001 - 10,000 BTU Moderate Anti-MAG result
> 10,000 BTU Significant anti-MAG result