LGI1 & CSPR2 Ab

Test investigation

LGI1 & CSPR2 Ab

Laboratory offering test

Referral laboratory

Also known as/Frequency of test

Voltage gated K+ antibodies NM; Voltage gated K+ channel complex antibodies,

Indications

Potassium channel antibodies are found in patients with acquired neuromyotonia (40-50%), Morvan's syndrome, limbic encephalitis and facio-brachial dystonic seizures (FBDS). There is an association with thymoma or small cell lung carcinoma (SCLC). LG1 and CASPR2 are the most common complex components associated with disease but the VGKC is the recommended screening test.

Comments precautions

Neurology request only. Referred outside of EPA

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

3 weeks

Reference intervals

Negative