Infliximab Level and Ab


Infliximab Level and Ab

Site(s) or Laboratory offering Test/Investigation

Referral laboratory



Also Known as/Frequency of Test

Remicade; Remsima; Inflectra, ADA – Anti-Drug antibodies


Diseases such as ulcerative colitis and Crohn’s disease respond to anti-Tumour Necrosis Factor alpha (TNF-α) therapy (e.g. Adalimumab/ infliximab). During treatment some patients can generate high levels of anti-drug antibodies (ADAs) which negate therapeutic effect. The serum concentration of the drug immediately prior to re-infusion (trough level) is needed to interpret the relevance of ADAs. Please refer to specialty guidelines for monitoring.

Sample type


Turnaround times (TAT) Urgent/Routine/GP or OPD

2 weeks

Reference intervals (adult unless stated)

>2.0 µg/mL
Therapeutic values for Adalimumab (or biosimilar) vary according to pathology