Ganglioside antibodies

Test investigation

Ganglioside antibodies

Laboratory offering test

Referral laboratory

Units

%

Also known as/Frequency of test

Anti- Ganglioside antibodies, GANG, GM1, GQ1b

Indications

Associated with several immunologically mediated peripheral neuropathies e.g. anti-GM1 (IgM) with multifocal motor neuropathy, GQ1b (IgG) with the Miller-Fisher syndrome and GM1 (IgG) with the Guillain-Barre syndrome. NB they can be found at low titres in healthy individuals.

Comments precautions

Referred outside of EPA

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 weeks

Reference intervals

<30% Negative 30 – 50% Grey Zone 51 – 100% Positive >100% Strongly Positive