GAD

Test investigation

GAD

Laboratory offering test

Referral laboratory

Units

IU/mL

Also known as/Frequency of test

GAD65, glutamic acid decarboxylase

Indications

Antibodies to glutamic acid decarboxylase (anti-GAD) are reliable serological markers of Insulin-dependent diabetes mellitus. Anti-GAD antibodies in high titre are associated with the stiff-person syndrome (60% sensitivity), a rare neurological disease characterised by muscle rigidity and spasms.

Comments precautions

Neurology/Endocrinology only. Referred outside of EPA.

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 weeks

Reference intervals

0 – 9 IU/mL