GAD

Test/Investigation

GAD

Site(s) or Laboratory offering Test/Investigation

Referral laboratory

Units

IU/mL

Also Known as/Frequency of Test

GAD65, glutamic acid decarboxylase

Indications

Antibodies to glutamic acid decarboxylase (anti-GAD) are reliable serological markers of Insulin-dependent diabetes mellitus. Anti-GAD antibodies in high titre are associated with the stiff-person syndrome (60% sensitivity), a rare neurological disease characterised by muscle rigidity and spasms.

Comments/Precautions

Neurology/Endocrinology only. Referred outside of EPA.

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 weeks

Reference intervals (adult unless stated)

0 – 9 IU/mL