Fibrillarin

Test investigation

Fibrillarin

Laboratory offering test

NNUH

Units

U/ml

Indications

Anti-Fibrillarin antibodies are seen in 5% of patients with diffuse systemic scleroderma and are associated with muscle disease and pulmonary hypertension. Consider discussing this patient with your local Rheumatologists if the patient has features of connective tissue disease.

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 working days

Reference intervals

0.0 – 7.0 U/ml Negative 7.0– 10.0 U/mL Equivocal >10 U/mL Positive