Centromere antibodies

Test investigation

Centromere antibodies

Laboratory offering test

NNUH

Units

U/ml

Also known as/Frequency of test

CENP; CENPB; ANA

Indications

Seen in 55-70% of patients with Limited Systemic Scleroderma, and in 15% of those with the diffuse form. The specificity of this test is >98%.

Comments precautions

Performed as part of ANA (see above)

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 working days

Reference intervals

0.0 – 7.0 U/ml Negative 7.0– 10.0 U/mL Equivocal >10 U/mL Positive