Autoimmune encephalitis syndromes = NMDAR, GlyR, GABA A/B, LG1/CASPR2, AMPAR

Test investigation

Autoimmune encephalitis syndromes = NMDAR, GlyR, GABA A/B, LG1/CASPR2, AMPAR

Laboratory offering test

Referral laboratory

Also known as/Frequency of test

NMDAR, N-methyl-D-aspartate (NMDA) receptor antibodies

Indications

Associated with immunotherapy-responsive autoimmune encephalitis. Different antibodies correlate with variable clinical syndromes and can indicate an underlying tumour.

Comments precautions

NMDA - Fixed cell and live cell assays are available, Fixed cell assay has a higher sensitivity and is the first line test. Please discuss with immunology if a live cell assay is required. Referred outside EPA.

Sample type

Serum/CSF

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 Weeks

Reference intervals

Negative