ANCA

Test investigation

ANCA

Laboratory offering test

NNUH

Units

IU/mL

Also known as/Frequency of test

Neutrophil Cytoplasmic Antibodies, MPO/PR3; c-ANCA; p-ANCA

Indications

MPO and PR3 antibodies are associated with the systemic necrotising vasculitides Granulomatous Polyangitis (GPA/Wegener's Granulomatosis), Microscopic Polyarteritis, Rapidly Progressive Glomerulonephritis and Churg-Strauss Syndrome

Comments precautions

MPO PR3 ANCA immunofluorescence

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 working days

Reference intervals

MPO <3.5 IU/mL Negative 3.5 – 5.0 IU/mL Equivocal >5.0 IU/mL Positive. PR3 <2.0 IU/mL Negative 2.0 – 3.0 IU/mL Equivocal >3.0 IU/mL Positive ANCA immunofluorescence Negative