Test/Investigation
Alkaline Phosphatase (ALP)
Site(s) or Laboratory offering Test/Investigation
NNUH, QEH, JPUH
Units
U/L
Comments/Precautions
Elevated in bone and liver disease (naturally elevated in children and pregnancy).
Sample type
Serum
Turnaround times (TAT) Urgent/Routine/GP or OPD
1 hour / 4 hour / by 8am next day
Reference intervals (adult unless stated)
Adults (18 years and over) 30 – 130 U/L
Male & Female:
0 – 14 day 90 – 273 U/L
15 – 365 day 134 – 518 U/L
1 – 9 yr 156 – 369 U/L
10 – 12 yr 141 – 460 U/L
Male:
13 – 14 yr 127 – 517 U/L
15 – 16 yr 89 – 365 U/L
17 – 18 yr 59 – 164 U/L
Female:
13 – 14 yr 62 – 280 U/L
15 – 16 yr 54 – 128 U/L
17 – 18 yr 48 – 95 U/L
If UKAS Accredited Test indicate at which site
Y NNUH, QEH
Source
Adult ranges: Pathology Harmony [Pathology Harmony Group, Clinical Biochemistry Outcomes, January 2011] https://www.acb.org.uk/asset/EEA82309-7E93-417D-9B8991B0C65C52FB/; accessed 09/11/2021 Paediatric ranges: CALIPER (Adeli, K., Higgins, V., Trajcevski, K., White-Al Habeeb, N. (2017). The Canadian laboratory initiative on pediatric reference intervals: A CALIPER white paper. Crit Rev Clin Lab Sci, 54(6):358-413. doi: 10.1080/10408363.2017.1379945. Epub 2017 Oct 11. Erratum in: Crit Rev Clin Lab Sci. 2020 Mar;57(2):145. PMID: 29017389.)