A1AT

Test/Investigation

A1AT

Site(s) or Laboratory offering Test/Investigation

NNUH

Units

g/L

Also Known as/Frequency of Test

Alpha-1-Antitrypsin

Indications

Measurement of AAT is indicated in the investigation of chronic obstructive airway disease, emphysema and in neonatal and adult liver disease where low concentrations may have diagnostic importance. Note: A1AT is an acute phase protein and may rise during infection and mask an underlying deficiency.

Comments/Precautions

Low alpha-1 regions on electrophoresis will prompt a request for an A1AT level.

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 working days

Reference intervals (adult unless stated)

0.9 – 2.0 g/L

If UKAS Accredited Test indicate at which site

Y NNUH